remains doubtful. In women Big Gainz Big Gainz produced through the ovaries fluctuates for the duration of the menstrual cycle, the highest amount being produced, together with estrogen, at ovulation. Androgen insufficiency in ladies has also been observed to be associated with hypopituitarism (deficiency of pituitary hormones), adrenal insufficiency, ovarian failure, and oophorectomy (the surgical removal of the many years used hormones to deal with the symptoms of both herbal and surgical menopause..